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💉 Health Tool

Semaglutide Calculator
Dosage & Mixing Guide

Calculate reconstitution volumes, units to inject, and days supply for compounded semaglutide. Educational use only.

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Educational Tool Only: Always follow your healthcare provider's instructions. Do not use this to self-prescribe medications. Dosing must be determined by a licensed medical professional.

💉Syringe type: Insulin syringe (1 mL = 100 units) — most common for subcutaneous injection

Semaglutide Dosage Calculator: Mixing & Injection Guide

This semaglutide dosage calculator helps you determine the correct reconstitution volumes and units to inject when using compounded semaglutide. Whether you have a 1mg, 2mg, 5mg, or 10mg vial and are adding bacteriostatic water, this tool calculates your concentration, volume per dose in mL, and units on an insulin syringe — all in seconds.

Important: This calculator is for educational purposes only. Always consult your prescribing healthcare provider or compounding pharmacy for exact dosing instructions. Never adjust your dose without medical supervision.

Semaglutide Reconstitution Formulas

Concentration (mg/mL) = Vial mg ÷ Water added (mL)

Volume per dose (mL) = Prescribed dose (mg) ÷ Concentration (mg/mL)

Units to inject = Volume (mL) × 100

Doses per vial = Vial mg ÷ Prescribed dose (mg)

Days supply = Doses per vial × 7

Standard Semaglutide Escalation Schedule

PhaseWeekly DosePurpose
Week 1–40.25mgInitial/Tolerance dose
Week 5–80.5mgMaintenance escalation
Week 9–121.0mgTherapeutic dose
Week 13–161.7mgHigher therapeutic dose
Week 17+2.4mgMaximum approved dose (Wegovy)

Note: Escalation schedules vary by prescriber and individual tolerance. Follow your provider's instructions.

How to Use This Semaglutide Calculator

  1. Select your vial size — Choose the total mg in your compounded semaglutide vial.
  2. Enter water volume — Select how many mL of bacteriostatic water you will add (per your pharmacy's instructions).
  3. Enter your prescribed dose — Select your prescribed weekly dose in mg.
  4. Click Calculate — View your concentration, volume per dose, units to inject, and days supply.
  5. Check the escalation table — See units at every dose level for easy reference.

Frequently Asked Questions

What is semaglutide?▾
Semaglutide is a GLP-1 receptor agonist medication approved for type 2 diabetes management and chronic weight management. It is sold under brand names Ozempic (for diabetes) and Wegovy (for weight loss). It works by mimicking the natural GLP-1 hormone to reduce appetite and regulate blood sugar. Compounded semaglutide is also available through compounding pharmacies at various doses.
How do you mix compounded semaglutide?▾
Compounded semaglutide typically comes as a lyophilized (freeze-dried) powder in a vial. To reconstitute, you inject bacteriostatic water into the vial using a sterile syringe, swirl gently (do not shake), and allow it to dissolve. Always follow your compounding pharmacy's specific instructions and your healthcare provider's guidance. The concentration depends on the amount of water added relative to the total mg in the vial.
How many units of semaglutide is 0.25mg?▾
The number of units depends entirely on the concentration of your reconstituted solution. For example, if you have a 2mg vial reconstituted with 2mL of bacteriostatic water, the concentration is 1 mg/mL. A 0.25mg dose would then be 0.25mL, or 25 units on an insulin syringe. Use this calculator to find the exact units for your specific vial and water volume combination.
What is the standard semaglutide dosing schedule?▾
The standard escalation schedule starts at 0.25mg per week for weeks 1–4, increases to 0.5mg for weeks 5–8, then 1mg for weeks 9–12. For weight management (Wegovy protocol), further escalation to 1.7mg and then 2.4mg may follow. This gradual escalation minimizes gastrointestinal side effects. Always follow your prescriber's specific instructions, as protocols may vary.
Is compounded semaglutide the same as Ozempic?▾
Compounded semaglutide contains the same active ingredient (semaglutide) as Ozempic and Wegovy, but it is not the same product. Compounded versions are not FDA-approved and have not gone through the same clinical testing, manufacturing standards, and quality controls as brand-name products. The FDA has raised concerns about the safety and purity of compounded semaglutide. Consult your healthcare provider about the differences.

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